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Region: TX
City: Houston
Postal Code: 77092
Latitude: 29.830099105835
Longitude: -95.473899841309
Area Code: 713
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MTRR A66G Mutation Basics

The MTRR A66G mutation is a defect of the methionine synthase reductase gene. A mutation of the MTRR A66G gene results in poor methylation of vitamin B12. Serum B12 levels may be normal in MTRR A66G (+/+) or (+/-) individuals; however, the under-methylation of vitamin B12 may result in elevated homocysteine levels.

MTRR gene - mutations and nutrition information - Gene Food

5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR) is an enzyme which interacts with methionine synthase, to ensure the continued production of the essential amino acid methionine, and is encoded for by the MTRR gene 1.. Methionine is an essential amino acid and is required for numerous processes throughout the body.

MTRR gene - Genetics Home Reference - NIH

The MTRR gene provides instructions for making an enzyme called methionine synthase reductase. This enzyme is required for the proper function of another enzyme called methionine synthase. Methionine synthase helps process amino acids, which are the building blocks of proteins.

MTR / MTRR – Homocysteine, methionine, and B12

MTR / MTRR – Homocysteine, methionine, and B12. Posted on July 7, 2015 by Debbie Moon 6 Comments. MTR (methionine synthase) and MTRR (methionine synthase reductase) are two genes involved in the conversion of homocysteine to methionine, and a couple of fairly common gene variants cause the genes to work differently. 6 Comments on “ MTR

MTRR and Vitamin B12 Impact Your Homocysteine – Suzy Cohen

So MTRR turns on the first enzyme, which then turns on the second enzyme, when then converts homocysteine into something user friendly in the body, i.e. methionine. This MTRR gene activity and enzyme sequences turns on and off as the body needs but stalls out when vitamin B12 is depleted.

MTR/MTRR Gene Mutation Symptoms, Testing and Treatments

What are MTR/MTRR gene mutations? MTRR (Methionine synthase reductase) helps recycle B12. The combination of MTR and MTRR mutations can deplete methyl B12. MTR A2756G, MTRR A66G, MTRR H595Y, MTRR K350A, MTRR R415T, MTRR S257T, and MTRR A664A all work together to convert homocysteine to methionine.

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