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Found 49 Websites with content related to this domain, It is result after search with search engine

General Schedule Supervisory Guide   DA: 11 PA: 50 MOZ Rank: 61

General Schedule Supervisory Guide HRCD-5 June 1998, April 1998 OTHER DEFINITIONS PROGRAM - The mission, functions, projects, activities, laws, rules, and regulations which an

Research Growing Spine Foundation (GSF)   DA: 20 PA: 9 MOZ Rank: 30

  • Why was the GSSG developed? The GSSG was initiated through educational tutorials and multicenter data collection in 2002 in response to a growing interest about improving treatment options for early onset scoliosis
  • The group’s first scientific project was presented at the Scoliosis Research Society’s annual meeting in 2003.

Guatemalan Student Support Group – Leading The Way To   DA: 12 PA: 12 MOZ Rank: 26

  • The Guatemalan Student Support Group (GSSG) is a small non-profit started in 2003 and headquartered in the Research Triangle area of North Carolina
  • Its purpose is to identify promising Guatemalan students and offer them scholarships to college, and, in some cases, high school
  • At present, GSSG students are obtaining college degrees in such

Policy, Data, Oversight : Classification & Qualifications   DA: 11 PA: 50 MOZ Rank: 64

  • The GSSG is a cross-series guide used to determine the grade level of supervisory work in the General Schedule
  • The GSSG has six evaluation factors, each with several factor-level definitions and corresponding point values
  • Work is evaluated by crediting the points designated for the highest level met under each factor, and converting the total


  • Although the GSSG requires no specific format for covered positions, users are not precluded from describing positions in a format that is compatible with that of the GSSG
  • Current core document system users also have an appropriate format available within the system.

Fish And Wildlife Service, Join Us And Grow, Classifying   DA: 11 PA: 36 MOZ Rank: 52

  • The GSSG uses a point-factor evaluation approach with six evaluation factors designed specifically for supervisory positions
  • The general classification concepts, principles, and policies used in determining non-supervisory GS positions also apply for supervisory positions
  • However, supervisory positions use the GSSG format rather than the

Pro-oxidant Shift In Glutathione Redox State During Aging   DA: 23 PA: 10 MOZ Rank: 39

  • The GSH:GSSG ratio, which is the primary determinant of the cellular redox state, becomes progressively more pro-oxidizing during the aging process due to an elevation in the GSSG content and a decline in the ability for de novo GSH biosynthesis
  • The K(m) of glutamate-cysteine ligase (GCL), the rate …

Glutathione Reductase   DA: 16 PA: 27 MOZ Rank: 50

Glutathione reductase (GR) also known as glutathione-disulfide reductase (GSR) is an enzyme that in humans is encoded by the GSR gene.Glutathione reductase (EC catalyzes the reduction of glutathione disulfide to the sulfhydryl form glutathione (), which is a critical molecule in resisting oxidative stress and maintaining the reducing environment of the cell.

TECHNICAL MANUAL GSH/GSSG-Glo™ Assay   DA: 15 PA: 50 MOZ Rank: 73

  • This blocking step is followed by a reducing step that converts GSSG to GSH for quantification in the luminescent reaction scheme
  • The following is a typical assay scenario: 1
  • Cells in a multiwell plate are treated with test compounds or vehicle: one set of cells for total glutathione

Glutathione Assays Cell Biolabs   DA: 19 PA: 19 MOZ Rank: 47

  • Glutathione helps protect cells from free radical damage by acting as an antioxidant
  • Within cells, glutathione exists in reduced (GSH) and oxidized (GSSG) states
  • In healthy cells and tissue, more than 90% of the pool is in the reduced form (GSH) while less than 10% exists in the disulfide form (GSSG)
  • The GSH form acts as an electron donor and is thereby oxidized itself to the GSSG form.

GSSG Executive Committee Growing Spine Foundation (GSF)   DA: 20 PA: 34 MOZ Rank: 64

  • He is the Deputy Editor for Pediatrics for the Journal of Bone and joint Surgery, Deputy Editor of Spine Deformity, and a reviewer for many journals
  • He was a member of the GSSG Executive Committee from 2008 to 2009 and on the Board of Directors of the GSF since 2009.

Quantification Kit For Oxidized And Reduced Glutathione   DA: 20 PA: 50 MOZ Rank: 81

  • The GSSG/GSH Quantification Kit contains the reagent for GSH masking
  • GSH in a sample solution can be removed by adding the Masking reagent
  • Therefore, GSSG in the sample solution can be selectively determined by measuring the absorption (λmax = 412 nm) derived from a colorimetric reaction of DTNB (5,5’-dithiobis (2-nitrobenzoic acid

Glutathione Synthesis In Cancer Cells   DA: 23 PA: 10 MOZ Rank: 45

  • Tripeptide GSH is associated not only with the control and maintenance of redox cell homeostasis, but also with the processes of detoxification, proliferation, cell differentiation, and regulation of cell death
  • Disruptions in GSH synthesis and changes in the GSH/GSSG ratio are common for many patho …

Glutathione Disulfide Liposomes   DA: 20 PA: 16 MOZ Rank: 49

  • At 1 mg/mL, the GSSG liposomes effectively increased intracellular GSSG by 27.1 ± 6.9 folds (n = 3) in 4 hours and led to a significant increase in protein S-glutathionylation confirming that the increased GSSG is functionally effective
  • The Trypan blue assay demonstrated that GSSG liposomes were not cytotoxic; the cell viability was greater


  • The incumbent provides leadership and direction while managing the work efforts of a diverse staff with a base level of non-supervisory work at the GS-13 grade level (>50%)
  • Using the Base Level Chart in the GSSG, page 23, this results in the assignment of Factor Level 5-8
  • Factor level 5-8, 1030 points is assigned

OPM Definitions Of Team Leader, Manager & Supervisor   DA: 12 PA: 50 MOZ Rank: 77

Under the GSSG (Manager Level 2 - Supervisor or Manager), the duties/responsibilities must also include the following "directs the work of an organizational unit, are held accountable for the success of specific line or staff functions, monitor and evaluate the progress of the organization toward meeting

Glutathione Cofactors: What They Are And Why They Are Needed   DA: 27 PA: 27 MOZ Rank: 70

  • In addition to the sufficient amounts of precursors, certain glutathione cofactors are required for the optimal functioning of the whole glutathione system
  • These cofactors are vitamin C, vitamin E, vitamins B1, B2, B6, B12, folate (B9), minerals …

GSH/GSSG-Glo™ Assay Measure Ratio Of GSH To GSSG Promega   DA: 15 PA: 50 MOZ Rank: 82

  • GSH (Panel A) and GSSG (Panel B) standards were assayed in a 96-well plate using the GSH/GSSG-Glo™ Assay and a GloMax® Luminometer.The results were averaged and plotted on the graphs above
  • A linear trend line was generated and correlation coefficients calculated …

The Copper(II)‐Catalyzed Oxidation Of Glutathione   DA: 40 PA: 31 MOZ Rank: 89

  • The 0.5 th reaction order with respect to O 2 reveals a pre-equilibrium prior to the rate-determining step of the GSSG formation
  • In contrast to [Cu 2+] and [O 2], the rate of the reactions decreases with increasing concentrations of GSH
  • This inverse relationship is proposed to be a result of the competing formation of an inactive form of the

Redox Regulation Of Ubiquitin-conjugating Enzymes   DA: 20 PA: 15 MOZ Rank: 54

Increases in the GSSG:GSH ratio from 0.02 in untreated cells to > or = 0.5 in diamide-treated cells were accompanied by dose-dependent reductions in the levels of endogenous Ub-protein conjugates, endogenous E1-ubiquitin thiol esters, and de novo ubiquitin-conjugating activity.

Single Probe, Deep Access Probe, Dual Probe, Set2Dil Probe   DA: 12 PA: 8 MOZ Rank: 40

  • GTL Microwave Probes were developed to provide superior electrical performance and unparalleled durability when used for probing on wafer, package, BGA, PCB, Socket, backplane, high density interconnect, etc
  • GTL Probes have a high tolerance, and the ruggedized probe tips allow them to land repeatedly, and take high quality data.

Glutathione Reductase From Baker's Yeast (S. Cerevisiae   DA: 20 PA: 26 MOZ Rank: 67

  • The GSSG is then recycled back to GSH by glutathione reductase (GR) using NADPH that is then converted to NADP +
  • The regenerated GSH is then available to detoxify more hydrogen peroxide
  • The enzyme uses FAD as a cofactor
  • GR and glutathione peroxidase may inhibit lipid peroxidation by functioning as antioxidant enzymes in sperm.

GSSG Definition Of GSSG By Medical Dictionary   DA: 40 PA: 5 MOZ Rank: 67

  • GSH levels in the yoga group increased significantly after completing the six month training period, while the GSSG levels decreased
  • Glutathione and total antioxidant status improved with yoga
  • Nine parts of blood were immediately (or at the indicated times)

GSSG – Galatea School   DA: 17 PA: 6 MOZ Rank: 46

  • The GSSG supports Galatea School through fundraising events…big and small
  • These events provide funds to support the school for things that education budgets don’t always allow for
  • Some things to date are the new resurfaced courts and nets, science kits, sports equipment, newly installed water fountains, maths Numicon resources in

The Fairytale Of The GSSG/GSH Redox Potential   DA: 21 PA: 42 MOZ Rank: 87

  • The relevance of the GSSG/GSH redox potential as driving force of biological processes is critically discussed
  • It is recalled that the concentration ratio of GSSG and GSH reflects little else than a steady state, which overwhelmingly results from fast enzymatic …

The GSH- And GSSG-bound Structures Of Glutaredoxin From   DA: 21 PA: 38 MOZ Rank: 84

  • The GSSG molecule is composed of two moieties, GS-1 and GS-2
  • (B) The GSSG-binding site of cGrx2
  • The binding site of GSSG is shown in stick models with the GSSG molecule in magenta and the cGrx2 residues in grey
  • The water molecules involved in …

The Copper(II)‐Catalyzed Oxidation Of Glutathione   DA: 40 PA: 32 MOZ Rank: 98

  • The 0.5 th reaction order with respect to O 2 reveals a pre-equilibrium prior to the rate-determining step of the GSSG formation
  • In contrast to [Cu 2+] and [O 2], the rate of the reactions decreases with increasing concentrations of GSH
  • This inverse relationship is proposed to be a result of the competing formation of an inactive form of the

GSSG/GSH Quantification Kit Dojindo Molecular   DA: 11 PA: 42 MOZ Rank: 80

  • The GSSG/GSH Quantification kit contains Masking Reagent of GSH
  • The GSH can be deactivated in the sample by simply adding the Masking Reagent
  • Therefore, temp-only the GSSG is detected by measuring the absorption (λmax = 412 nm) of DTNB (5,5 Edithiobis (2-nitrobenzoic acid) using the enzymatic recycling system.

Impairment Of Intestinal Glutathione Synthesis In Patients   DA: 11 PA: 17 MOZ Rank: 56

  • Background —Reactive oxygen species contribute to tissue injury in inflammatory bowel disease (IBD)
  • The tripeptide glutathione (GSH) is the most important intracellular antioxidant
  • Aims —To investigate constituent amino acid plasma levels and the GSH redox status in different compartments in IBD with emphasis on intestinal GSH synthesis in Crohn’s disease.

Role Of Glutathione In Cancer Progression And Chemoresistance   DA: 15 PA: 27 MOZ Rank: 71

  • Glutathione (GSH) plays an important role in a multitude of cellular processes, including cell differentiation, proliferation, and apoptosis, and disturbances in GSH homeostasis are involved in the etiology and progression of many human diseases including cancer
  • While GSH deficiency, or a decrease in the GSH/glutathione disulphide (GSSG) ratio, leads to an increased susceptibility to

RESEARCHARTICLE ContributionofFdh3andGlr1toGlutathione   DA: 17 PA: 21 MOZ Rank: 68

RESEARCHARTICLE ContributionofFdh3andGlr1toGlutathione RedoxState,StressAdaptationandVirulence inCandidaalbicans AnnaT.Tillmann1¤a,KarinStrijbis2¤b,GaryCameron3

3.1.9 Explore Reversible Reactions In Nature   DA: 18 PA: 50 MOZ Rank: 99

  • In addition, the GSSG and GSH were checked by NMR on a Varian XL-400 instrument prior to purification, because we have observed that glutathiones obtained from some suppliers contained significant amounts (in some cases >20%) of a-glutamyl cysteinyl glycine (M
  • Adler, D.M.R., and H.A.S., unpublished results) as well as cysteinylglycine (T

FAQ: Glutathione (GSSG/GSH) Assay Cell Biolabs   DA: 19 PA: 37 MOZ Rank: 88

  • The unknown samples will be plotted as OD vs
  • time, similar to the first graph
  • After calculating the net slope for each of the unknowns, the values are compared to the second graph (net slope vs
  • concentration of the standards) to determine the GSSG concentration for each unknown.

Antioxidants Free Full-Text Oxidative Stress In   DA: 12 PA: 20 MOZ Rank: 65

  • Oxidative stress plays a key role in the pathophysiology of chronic kidney disease (CKD)
  • Most studies have investigated peripheral redox state focus on plasma, but not in different immune cells
  • Our study analyzed several redox state markers in plasma and isolated peripheral polymorphonuclear (PMNs) and mononuclear (MNs) leukocytes from advanced-CKD patients, also evaluating differences …

GSSG Solar Announces Promotion Of Charlie McDaniel And   DA: 20 PA: 50 MOZ Rank: 16

“We have been fortunate to have both Adrian and Charlie providing their leadership for the GSSG Solar organization since our inception in 2013, and this promotion is a reflection of both their

Glutathione Metabolism And Its Implications For Health   DA: 16 PA: 29 MOZ Rank: 80

  • Glutathione synthesis and utilization in animals
  • Enzymes that catalyze the indicated reactions are: 1) γ-glutamyl transpeptidase, 2) γ-glutamyl cyclotransferase, 3) 5-oxoprolinase, 4) γ-glutamyl-cysteine synthetase, 5) glutathione synthetase, 6) dipeptidase, 7) glutathione peroxidase, 8) glutathione reductase, 9) superoxide dismutase, 10) BCAA transaminase (cytosolic and …

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